english DETERMINANTS OF ADHERENCE TO ANTI-TUBERCULOSIS DRUGS (ATD) AT BALOI PERMAI PRIMARY HEALTH CENTER, BATAM
DOI:
https://doi.org/10.54973/jham.v7i1.855Kata Kunci:
Tuberculosis, adherence, family support, health managementAbstrak
Adherence to anti-tuberculosis drugs (ATD) therapy is a critical determinant of successful tuberculosis treatment and the prevention of drug resistance. Non-adherence may lead to treatment failure, disease recurrence, and continued transmission within the community. Therefore, identifying factors that influence patient adherence is essential for strengthening tuberculosis control programs. This study aimed to examine factors associated with adherence to anti-tuberculosis medication among pulmonary tuberculosis patients at Baloi Permai Primary Health Center, Batam City. A quantitative cross-sectional study was conducted involving 39 patients undergoing anti-tuberculosis treatment. Data were collected using structured questionnaires assessing knowledge, attitudes, practices, family support, and the role of health workers. Statistical analysis was performed using Chi-square tests and logistic regression. The bivariate analysis revealed that patient attitude (p = 0.050) and family support (p = 0.006) were significantly associated with treatment adherence. Meanwhile, knowledge, practices, and the role of health workers were not significantly related to adherence (p > 0.05). Multivariate analysis identified family support as the most influential factor affecting adherence to anti-tuberculosis therapy (OR = 6.03; p = 0.010). In conclusion, family support is the strongest determinant of ATD adherence. Strengthening family-based approaches should be integrated into TB management programs at primary healthcare facilities.
Unduhan
Referensi
Adam. (2020). Pengetahuan Penderita Tuberkulosis Paru Terhadap Kepatuhan Minum Obat Anti Tuberkulosis. Jambura Health and Sport Journal, 2(1), doi: 10.37311/jhsj.v2i1.4560.
Alamsyah. (2025). Factors Associated with Adherence to Taking Medication in Tuberculosis Patients at Lawawoi Health Center, Sidenreng Rappang Regency. Jurnal Kesehatan, 18(2), 238–248.
Alsoukhni,Khader. (2023). Tuberculosis-related knowledge, behaviors, stigmatizing attitude, and discrimination among refugees, migrants, and the general population in Jordan. SAGE Open Med, vol. 11, doi: 10.1177/20503121231187743.
Andriani, L., (2023). Hubungan Tingkat Pengetahuan dan Dukungan Keluargadengan Kepatuhan Minum Obat pada Penderita Tuberkulosis di wilayah Kerja Puskesmas Pahandut. Jurnal Surya Medika (JSM), 9(10, 96-103. doi : https://doi.org./10.33084/jsm.v9i1.5155.
Anshar, D., et al. (2023). Correlation between family support and health professional education on tuberculosis patient compliance at public health centers Tasikmalaya. Jurnal Sains Farmasi & Klinis, 10(3), 314-319.
Arikunto, S. (2010). Prosedur Penelitian: Suatu Pendekatan Praktik. Rineka Cipta.
Arsyad. (2024). Hubungan Dukungan Keluarga dengan Kepatuhan Minum Obat pada Penderita Tuberkulosis Paru. Jurnal Keperawatan Wiyata, 5(2). doi: 10.29241/jmk.v7i1.605
Aryani, L., Manglapy, Y.(2021). Implikasi Faktor Individu Terhadap Stigma Sosial Tuberkulosis Di Kelurahan Tanjung Mas Semarang. Jurnal Manajemen Kesehatan Yayasan RS. Dr. Soetomo, 7(1), 90-104.
Dodiet Aditya Setyawan. (2022). Uji Validitas dan Realibilitas. in Www.Researchgate.Net, no. July, 2022.
Dwi, Setyo. (2024). Pengaruh Pengetahuan, Sikap, Dan Dukungan Dari Keluarga Terhadap Kepatuhan Pasien Tb Paru Dalam Menelan Obat Anti Tuberkulosis Di Wilayah Kerja Puskesmas Kedokanbunder Indramayu. Pro Health Jurnal Ilmiah Kesehatan. Vol. 6 (1). 20-27.
Fitriani, N. E., et al. (2019). Hubungan antara pengetahuan, motivasi pasien dan dukungan keluarga terhadap kepatuhan minum obat anti tuberkulosis (OAT) pada penderita penyakit TB paru BTA (+) di Puskesmas Pasundan Kota Samarinda. Kesmas Uwigama: Jurnal Kesehatan Masyarakat, 5(2), 124-128.
Friedman, M. M., Bowden, V. R., & Jones, E. G. (2010). Family nursing: Research, theory, and practice (5th ed.). Upper Saddle River, NJ: Prentice Hall.
Glanz, K., Rimer, B. K., & Viswanath, K. (2015). Health behavior: Theory, research, and practice (5th ed.). Jossey-Bass.
Green, L.W. & Kreuter, M.W. (2005). Health program planning: An educational and ecological approach. (4th ed.). McGraw-Hill.
Hasina, A. Rahmawati, I. (2023). Hubungan Tingkat Pengetahuan dengan Kepatuhan Minum Obat Anti Tuberkulosis (OAT) pada Pasien Tuberkulosis Paru. Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal, 13(2), doi: 10.32583/pskm.v13i2.908.
Herdianti, E. Entianopa, and S. Sugiarto. (2020). Effect Of Patient’s Personal Character On Prevention Of Transmission Of Pulmonary TB. Indonesian Journal of Tropical and Infectious Disease. doi: 10.20473/ijtid.v8i1.12318.
Herdianti, H. Oktarizal, E. Martha, F. Y. Sembiring, and F. Dinilhaq. (2025). Edukasi Dan Kampanye Pencegahan Penyakit Menular (HIV-AIDS dan TBC) Di Tempat Kerja. Puan Indonesia, 7(1). doi: 10.37296/jpi.v7i1.368.
Hermiati, Eka Joni Yansyah. (2024). Faktor Kepatuhan Minum Obat Pasien Dengan Tuberkulosis. Lentera Perawat, 5(1). doi: 10.52235/lp.v5i1.282.
House, J.S. (1981). Work, Stress, and Social Support. Addison-Wesley Publishing Company.
Jang and M. A. Lee. (2022). A study of relationships among tuberculosis knowledge, family support, and medication adherence in tuberculosis patients. Journal of Korean Academic Society of Nursing Education. 28(1). doi: 10.5977/jkasne.2022.28.1.80.
Jiangjing, Z. Meng, X. Zuhui, and Z. Chuanfang. (2025). Analysis of occupational satisfaction and associated factors among tuberculosis health management staff in primary healthcare institutions in Hunan Province. Chinese Journal of Antituberculosis, 47(7). doi: 10.19982/j.issn.1000-6621.20250020.
Kartiningrum, Eka. (2022). Aplikasi Regresi Dan Korelasi Dalam Analisis Data Penelitian. STIKes Majapahit Mojokerto. P32-50.
Kaumba et al., (2024). Knowledge, attitudes, and practices towards childhood tuberculosis among healthcare workers at two primary health facilities in Lusaka, Zambia. PLoS One, 19(3).doi: 10.1371/journal.pone.0287876.
Kementerian Kesehatan RI. (2021). Pedoman Nasional Penanggulangan Tuberkulosis. Jakarta: Kemenkes RI.
Kementerian Kesehatan RI. (2025). Buku Panduan Tenaga Medis Dan Tenaga Kesehatan Tuberkulosis. Langkah Dalam Pencegahan, Deteksi Dini, Dan Pendampingan Pasien TBC di Masyarakat .
Mariani et al. (2022). Tuberculosis Family Support Training’s (TB FaST) Influence on Encouraging TB Treatment Compliance. Open Public Health J, 15(1). doi: 10.2174/18749445-v15-e2208041.
Mariska. (2025). Peran Petugas Kesehatan dan Pengawas Minum Obat dengan Kepatuhan Minum Obat pada Pasien Tuberkulosis. Jurnal Keperawatan Florence Nightingale, 8(1). doi: 10.52774/jkfn.v8i1.381.
Mekar Sekuntum. (2024). Visi Dan Misi Presiden Dan Wakil Presiden Terpilih Periode2024-2029, Https://Mekarsekuntum.Simsa.Id/Artikel/2024/10/30/Visi-Dan-Misi- Presiden-Dan-Wakil-Presiden-Terpilih-Periode-2024-2029
Morisky, D. E., Ang, A., Krousel-Wood, M., & Ward, H. (2008).
Predictive validity of a medication adherence measure in an outpatient setting. The Journal of Clinical Hypertension, 10(5), 348-354. Kuesioner MMAS-8 (Morisky Medication Adherence Scale).
Munro, S. A., Lewin, S. A., Smith, H. J., Engel, M. E., Fretheim, A., & Volmink, J. (2007). Patient adherence to tuberculosis treatment: A systematic review of qualitative research. PLoS Medicine, 4(7), e238.
Nabila. (2023). Faktor-Faktor yang Mempengaruhi Kepatuhan Minum Obat Anti Tuberkulosis (OAT) pada Penderita Tuberkulosis Paru (TB) : Literature Review. Media Publikasi Promosi Kesehatan Indonesia (MPPKI), 6(8). doi: 10.56338/mppki.v6i8.3484.
Najah. (2022). Literatur Review Implementasi SDGs pada Kebutuhan Sehat dan Kesejahteraan. Jurnal Sains Edukatika Indonesia (JSEI), 4(1), 51-58.
Nezenega, Z. S., et al. (2020). Factors influencing patient adherence to tuberculosis treatment: a systematic review and synthesis. International Journal of Environmental Research and Public Health, 17(15), 5626.
Notoatmodjo, S. (2014). Ilmu perilaku kesehatan. Jakarta: Rineka Cipta. 26-33
Oh, H. J., Law, M. A., & Shamputa, I. C. (2025). Tuberculosis-related knowledge, attitudes, and practices among healthcare workers in Atlantic Canada: A descriptive study. Tropical Medicine Infectious Disease.10. 214
Puskesmas Baloi Permai. (2025). Profil Kesehatan Puskesmas Baloi Permai tahun 2024.
Samsi, L., Yuniarsih, S. (2023). Studi Kualitatif Peran Pemangku Kepentingan pada Pengobatan TB dalam Program Indonesia Sehat. Jurnal Manajemen Kesehatan Yayasan RS. Dr. Soetomo, 9(2), 233-248.
Sani, A. J. Hadi, and H. Hatta. (2025). Key Determinants of Tuberculosis Prevention Behaviors Among Families in Indonesia: A Cross-Sectional Study Analysis. Media Publikasi Promosi Kesehatan Indonesia, 8(2). doi: 10.56338/mppki.v8i2.6860.
Sarafino, E. P., & Smith, T. W. (2011). Health psychology: Biopsychosocial interactions (7th ed.). New York, NY: Wiley.
Saunders. (2025). The social determinants of tuberculosis: a case-control study characterising pathways to equitable intervention in Peru. Infect Dis Poverty, vol. 14, no. 1, 2025, doi: 10.1186/s40249-025-01324-6.
Sugiarto, H. Herdianti, and E. Entianopa (2018). Pengetahuan, Persepsi, Self Efficacy dan Pengaruh Interpersonal Penderita terhadap Pencegahan Penularan TB Paru (Descriptif Study). Gorontalo Journal of Public Health. doi: 10.32662/gjph.v1i2.274.
Susanto, A., Purwantingrum, H. (2022). Analisis Pengetahuan, Dukungan Keluarga dan Tenaga Kesehatan dengan Kepatuhan Penderita Hipertensi untuk Minum Obat. Jurnal Manajemen Kesehatan Yayasan RS. Dr. Soetomo, 8(2), 275-286. doi: 10.29241/jmk.v8i2.1022
WHO. (2020). Global Tuberculosis Report. World Health Organization.
Widiastutik, M. Makhfudli, and S. D. Wahyuni. (2020). Hubungan Dukungan Keluarga, Kader dan Petugas Kesehatan dengan Kepatuhan Berobat Penderita TB Paru. Indonesian Journal of Community Health Nursing. 5(1). doi: 10.20473/ijchn.v5i1.18654.
Widyastuti, S. D., et al. (2024). Pengaruh Pengetahuan, Sikap, dan Dukungan Dari Keluarga Terhadap Kepatuhan Pasien TB Paru dalam Menelan Obat Anti Tuberkulosis Di Wilayah Kerja Puskesmas Kedokanbunder Indramayu. Pro Health Jurnal Ilmiah Kesehatan, 6(1), 20–27.
